Results Generated From:
Embase <1980 to 2014 Week 43>
Embase (updates since 2014-10-17)
<1>
Accession Number
23737029
Authors
Khalil A. Suff N. Thilaganathan B. Hurrell A. Cooper D. Carvalho J.S.
Institution
(Khalil) Fetal Medicine Unit, St. George's Medical School, University of
London, London, UK.
Title
Brain abnormalities and neurodevelopmental delay in congenital heart
disease: systematic review and meta-analysis.
Source
Ultrasound in obstetrics & gynecology : the official journal of the
International Society of Ultrasound in Obstetrics and Gynecology. 43 (1)
(pp 14-24), 2014. Date of Publication: Jan 2014.
Abstract
Studies have demonstrated an association between congenital heart disease
(CHD) and neurodevelopmental delay. Neuroimaging studies have also
demonstrated a high incidence of preoperative brain abnormalities. The aim
of this study was to perform a systematic review to quantify the
non-surgical risk of brain abnormalities and of neurodevelopmental delay
in infants with CHD. MEDLINE, EMBASE and The Cochrane Library were
searched electronically without language restrictions, utilizing
combinations of the terms congenital heart, cardiac, neurologic,
neurodevelopment, magnetic resonance imaging, ultrasound, neuroimaging,
autopsy, preoperative and outcome. Reference lists of relevant articles
and reviews were hand-searched for additional reports. Cohort and
case-control studies were included. Studies reporting neurodevelopmental
outcomes and/or brain lesions on neuroimaging in infants with CHD before
heart surgery were included. Cases of chromosomal or genetic
abnormalities, case reports and editorials were excluded. Between-study
heterogeneity was assessed using the I(2) test. The search yielded 9129
citations. Full text was retrieved for 119 and the following were included
in the review: 13 studies (n = 425 cases) reporting on brain abnormalities
either preoperatively or in those who did not undergo congenital cardiac
surgery and nine (n = 512 cases) reporting preoperative data on
neurodevelopmental assessment. The prevalence of brain lesions on
neuroimaging was 34% (95% CI, 24-46; I(2) = 0%) in transposition of the
great arteries, 49% (95% CI, 25-72; I(2) = 65%) in left-sided heart
lesions and 46% (95% CI, 40-52; I(2) =18.1%) in mixed/unspecified cardiac
lesions, while the prevalence of neurodevelopmental delay was 42% (95% CI,
34-51; I(2) = 68.9). In the absence of chromosomal or genetic
abnormalities, infants with CHD are at increased risk of brain lesions as
revealed by neuroimaging and of neurodevelopmental delay. These findings
are independent of the surgical risk, but it is unclear whether the time
of onset is fetal or postnatal. Copyright 2013 ISUOG. Published by John
Wiley & Sons Ltd.
<2>
Accession Number
2014822856
Authors
Silverberg S.J. Clarke B.L. Peacock M. Bandeira F. Boutroy S. Cusano N.E.
Dempster D. Lewiecki E.M. Liu J.-M. Minisola S. Rejnmark L. Silva B.C.
Walker M.D. Bilezikian J.P.
Institution
(Silverberg, Cusano, Dempster, Walker, Bilezikian) Columbia University,
College of Physicians and Surgeons, 630 West 168th Street, PH 8W-864, New
York, NY 10032, United States
(Clarke) Mayo Clinic, Rochester, MN 55902, United States
(Peacock) Indiana University, School of Medicine, Indianapolis, IN 46202,
United States
(Bandeira) University of Pernambuco, School of Medicine, Recife 52050-450,
Brazil
(Boutroy) INSERM UMR 1033, Universite de Lyon, Lyon 69437, France
(Lewiecki) New Mexico Clinical Research and Osteoporosis Center,
University of New Mexico, School of Medicine, Albuquerque, NM 87106,
United States
(Liu) Shanghai Jiao-tong University, School of Medicine, Shanghai 200025,
China
(Minisola) Sapienza University of Rome, Rome 00161, Italy
(Rejnmark) Aarhus University Hospital, Aarhus 8000, Denmark
(Silva) Federal University of Minas Gerais, Belo Horizonte 30.130-100,
Brazil
Title
Current issues in the presentation of asymptomatic primary
hyperparathyroidism: Proceedings of the fourth International Workshop.
Source
Journal of Clinical Endocrinology and Metabolism. 99 (10) (pp 3580-3594),
2014. Date of Publication: 01 Oct 2014.
Publisher
Endocrine Society
Abstract
Consensus Process: Questions were developed by the International Task
Force on PHPT. A comprehensive literature search for relevant studies was
undertaken. After extensive review and discussion, the subgroup came to
agreement on what changes in the recommendations for surgery or
nonsurgical follow-up of asymptomatic PHPT should be made to the Expert
Panel.
<3>
Accession Number
2014824909
Authors
Holmes M.V. Frikke-Schmidt R. Melis D. Luben R. Asselbergs F.W. Boer
J.M.A. Cooper J. Palmen J. Horvat P. Engmann J. Li K.-W. Onland-Moret N.C.
Hofker M.H. Kumari M. Keating B.J. Hubacek J.A. Adamkova V. Kubinova R.
Bobak M. Khaw K.-T. Nordestgaard B.G. Wareham N. Humphries S.E. Langenberg
C. Tybjaerg-Hansen A. Talmud P.J.
Institution
(Holmes, Keating) Department of Surgery, Division of Transplantation,
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA,
United States
(Holmes, Horvat, Engmann, Kumari, Bobak, Langenberg) Department of
Epidemiology and Public Health, University College London, London, United
Kingdom
(Frikke-Schmidt, Tybjaerg-Hansen) Department of Clinical Biochemistry,
Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
(Nordestgaard, Tybjaerg-Hansen) The Copenhagen City Heart Study,
Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen,
Denmark
(Frikke-Schmidt, Nordestgaard, Tybjaerg-Hansen) The Copenhagen General
Population Study, Herlev Hospital, Copenhagen University Hospital,
Copenhagen, Denmark
(Frikke-Schmidt, Nordestgaard, Tybjaerg-Hansen) Faculty of Health and
Medical Sciences, University of Copenhagen, Copenhagen, Denmark
(Melis, Cooper, Palmen, Li, Humphries, Talmud) Centre for Cardiovascular
Genetics, Institute of Cardiovascular Science, University College London,
London, United Kingdom
(Luben, Khaw) Department of Public Health and Primary Care, University of
Cambridge, Cambridge, United Kingdom
(Asselbergs) Department of Cardiology, Division Heart and Lungs,
University Medical Center, Utrecht, Netherlands
(Asselbergs) Durrer Center for Cardiogenetic Research, ICIN-Netherlands
Heart Institute, Utrecht, Netherlands
(Asselbergs) Institute of Cardiovascular Science, Faculty of Population
Health Sciences, University College London, London, United Kingdom
(Boer) Centre for Nutrition, Prevention and Health Services, National
Institute for Public Health and the Environment, PO Box 1, BA Bilthoven
3720, Netherlands
(Onland-Moret) Julius Center for Health Sciences and Primary Care,
University Medical Center, Utrecht, Netherlands
(Hofker) Department of Pediatrics, Molecular Genetics, University Medical
Center Groningen, Groningen University, Groningen, Netherlands
(Hubacek, Adamkova) Center for Experimental Medicine, Institute for
Clinical and Experimental Medicine, Videnska 1958/9, Prague 4 14021, Czech
Republic
(Kubinova) National Institute of Public Health, Srobarova 48, Prague
10042, Czech Republic
(Nordestgaard, Wareham) Department of Clinical Biochemistry, Herlev
Hospital, Copenhagen University Hospital, Copenhagen, Denmark
(Langenberg) MRC Epidemiology Unit, Institute of Metabolic Science,
University of Cambridge, United Kingdom
Title
A systematic review and meta-analysis of 130,000 individuals shows smoking
does not modify the association of APOE genotype on risk of coronary heart
disease.
Source
Atherosclerosis. 237 (1) (pp 5-12), 2014. Date of Publication: December
01, 2014.
Publisher
Elsevier Ireland Ltd
Abstract
Background: Conflicting evidence exists on whether smoking acts as an
effect modifier of the association between APOE genotype and risk of
coronary heart disease (CHD). Methods and results: We searched PubMed and
EMBASE to June 11, 2013 for published studies reporting APOE genotype,
smoking status and CHD events and added unpublished data from population
cohorts. We tested for presence of effect modification by smoking status
in the relationship between APOE genotype and risk of CHD using likelihood
ratio test.In total 13 studies (including unpublished data from eight
cohorts) with 10,134 CHD events in 130,004 individuals of European descent
were identified. The odds ratio (OR) for CHD risk from APOE genotype (4
carriers versus non-carriers) was 1.06 (95% confidence interval (CI):
1.01, 1.12) and for smoking (present vs. past/never smokers) was OR 2.05
(95%CI: 1.95, 2.14). When the association between APOE genotype and CHD
was stratified by smoking status, compared to non-4 carriers, 4 carriers
had an OR of 1.11 (95%CI: 1.02, 1.21) in 28,789 present smokers and an OR
of 1.04 (95%CI 0.98, 1.10) in 101,215 previous/never smokers, with no
evidence of effect modification (. P-value for heterogeneity=0.19).
Analysis of pack years in individual participant data of >60,000 with
adjustment for cardiovascular traits also failed to identify evidence of
effect modification. Conclusions: In the largest analysis to date, we
identified no evidence for effect modification by smoking status in the
association between APOE genotype and risk of CHD.
<4>
Accession Number
2014602476
Authors
Song B.-h. Jiang P.-j. Wang Z.-h.
Institution
(Song) Anesthesiology Department, Xinjiang Cardiovascular and
Cerebrovascular Hospital, Urumqi 830054, China
(Jiang) Anesthesiology Department, Fangcaohu Hospital of the Sixth
Xinjiang Construction Corps, Fangcaohu 831100, China
(Wang) People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi
830054, China
Title
Clinical effects of strict control versus conventional control of blood
glucose on perioperative cardiac surgery: A meta-analysis.
Source
Chinese Journal of Evidence-Based Medicine. 12 (10) (pp 1229-1234), 2012.
Date of Publication: 2012.
Abstract
Objective To evaluate clinical effects of strict control vs. conventional
control of blood glucose in perioperative cardiac surgery. Methods
Databases including PubMed, EMbase, HighWire, The Cochrane Library, CBM
and VIP were searched to collect the randomized controlled trials (RCTs)
on strict control vs. conventional control of blood glucose in
perioperative cardiac surgery, published from 2000 to 2011. Two reviewers
independently screened articles according to the inclusion and exclusion
criteria, extracted data, and assessed quality of the included studies.
Then metaanalysis was performed using RevMan 5.1. Results A total of 8
RCTs involving 2 250 patients were included. The results of meta-analysis
showed that compared with the conventional group, the strict control of
blood glucose could reduce postoperative short-term mortality (OR=0.52,
95% CI 0.30 to 0.91, P=0.02) and postoperative incidence rate of both
atrial fibrillation (OR=0.64, 95%CI 0.43 to 0.96, P=0.03) and incision
infection (OR=0.30, 95%CI 0.15 to 0.57, P=0.000 2), and shorten hospital
stay (MD=1.75, 95%CI -3.18 to -0.32, P<0.02) and time of mechanical
ventilation (MD= -0.9, 95%CI -1.43 to -0.38, P<0.000 8). Conclusion
Current evidence shows that the strict control of blood glucose in
perioperative cardiac surgery can reduce postoperative short-term
mortality and postoperative incidence rate of both atrial fibrillation and
incision infection, shorten hospital stay and time of mechanical
ventilation, and have important clinical values and social and economic
significance. However, this conclusion has to be proved by more
high-quality and large-scale RCTs for the limitation of quantity and
quality of the included studies. 2012 Editorial Board of Chin J
Evid-based Med.
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