Saturday, November 1, 2014

EMBASE Cardiac Update AutoAlert: EPICORE Cardiac Surgery Blogger2

Total documents retrieved: 11

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Embase <1980 to 2014 Week 44>
Embase (updates since 2014-10-23)


<1>
Accession Number
2014791119
Authors
Mathiesen O. Wetterslev J. Kontinen V.K. Pommergaard H.-C. Nikolajsen L.
Rosenberg J. Hansen M.S. Hamunen K. Kjer J.J. Dahl J.B.
Institution
(Mathiesen) Section of Acute Pain Management, Rigshospitalet, Copenhagen
University Hospital, Copenhagen, Denmark
(Wetterslev) Copenhagen Trial Unit, Rigshospitalet, Copenhagen University
Hospital, Copenhagen, Denmark
(Kontinen) Department of Anaesthesia and Intensive Care, Helsinki
University Central Hospital, Helsinki, Finland
(Pommergaard, Rosenberg) Department of Surgery, Herlev Hospital,
University of Copenhagen, Herlev, Denmark
(Nikolajsen) Department of Anaesthesiology, Aarhus University Hospital,
Aarhus, Denmark
(Hansen, Dahl) Department of Anaesthesiology, Rigshospitalet, Copenhagen
University Hospital, Copenhagen, Denmark
(Hamunen) Pain Clinic, Helsinki University Central Hospital, Helsinki,
Finland
(Kjer) Department of Gynecology, Rigshospitalet, Copenhagen University
Hospital, Copenhagen DK-2100, Denmark
Title
Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids,
gabapentinoids and their combinations: A topical review.
Source
Acta Anaesthesiologica Scandinavica. 58 (10) (pp 1182-1198), 2014. Date of
Publication: 01 Nov 2014.
Publisher
Blackwell Munksgaard
Abstract
Post-operative pain affects millions of patients worldwide and the
post-operative period has high rates of morbidity and mortality. Some of
this morbidity may be related to analgesics. The aim of this review was to
provide an update of current knowledge of adverse events (AE) associated
with the most common perioperative non-opioid analgesics: paracetamol,
non-steroidal anti-inflammatory drugs (NSAIDs), glucocorticoids (GCCs),
gabapentinoids and their combinations. The review is based on data from
systematic reviews with meta-analyses of analgesic efficacy and/or adverse
effects of perioperative non-opioid analgesics, and randomised trials and
cohort/retrospective studies. Generally, data on AE are sparse and related
to the immediate post-operative period. For paracetamol, the incidence of
AEs appears trivial. Data are inconclusive regarding an association of
NSAIDs with mortality, cardiovascular events, surgical bleeding and renal
impairment. Anastomotic leakage may be associated with NSAID usage. No
firm evidence exists for an association of NSAIDs with impaired bone
healing. Single-dose GCCs were not significantly related to increased
infection rates or delayed wound healing. Gabapentinoid treatment was
associated with increased sedation, dizziness and visual disturbances, but
the clinical relevance needs clarification. Importantly, data on AEs of
combinations of the above analgesics are sparse and inconclusive. Despite
the potential adverse events associated with the most commonly applied
non-opioid analgesics, including their combinations, reporting of such
events is sparse and confined to the immediate perioperative period.
Knowledge of benefit and harm related to multimodal pain treatment is
deficient and needs clarification in large trials with prolonged
observation.

<2>
Accession Number
24626264
Authors
Perazzo A. Gatto P. Barlascini C. Ferrari-Bravo M. Nicolini A.
Institution
(Perazzo, Gatto, Nicolini) Department of Respiratory Diseases, Sestri
Levante General Hospital, Sestri Levante, Italy
(Barlascini) Department of Forensic Medicine, ASL4, Chiavarese, Italy
(Ferrari-Bravo) Department of Public Health, ASL4, Chiavarese, Italy
Title
Can ultrasound guidance reduce the risk of pneumothorax following
thoracentesis?.
Source
Jornal Brasileiro de Pneumologia. 40 (1) (pp 6-12), 2014. Date of
Publication: JANUARY/FEBRUARY 2014.
Abstract
Objective: Thoracentesis is one of the bedside procedures most commonly
associated with iatrogenic complications, particularly pneumothorax.
Various risk factors for complications associated with thoracentesis have
recently been identified, including an inexperienced operator; an
inadequate or inexperienced support team; the lack of a standardized
protocol; and the lack of ultrasound guidance. We sought to determine
whether ultrasoundguided thoracentesis can reduce the risk of pneumothorax
and improve outcomes (fewer procedures without fluid removal and greater
volumes of fluid removed during the procedures). In our comparison of
thoracentesis with and without ultrasound guidance, all procedures were
performed by a team of expert pulmonologists, using the same standardized
protocol in both conditions. Methods: A total of 160 participants were
randomly allocated to undergo thoracentesis with or without ultrasound
guidance (n = 80 per group). The primary outcome was pneumothorax
following thoracentesis. Secondary outcomes included the number of
procedures without fluid removal and the volume of fluid drained during
the procedure. Results: Pneumothorax occurred in 1 of the 80 patients who
underwent ultrasound-guided thoracentesis and in 10 of the 80 patients who
underwent thoracentesis without ultrasound guidance, the difference being
statistically significant (p = 0.009). Fluid was removed in 79 of the 80
procedures performed with ultrasound guidance and in 72 of the 80
procedures performed without it. The mean volume of fluid drained was
larger during the former than during the latter (960 + 500 mL vs. 770 +
480 mL), the difference being statistically significant (p = 0.03).
Conclusions: Ultrasound guidance increases the yield of thoracentesis and
reduces the risk of post-procedure pneumothorax.

<3>
Accession Number
2014838811
Authors
Costa Almeida C.E.P. Reis L. Carvalho L. Costa Almeida C.M.
Institution
(Costa Almeida, Reis, Carvalho, Costa Almeida) Centro Hospitalar e
Universitario de Coimbra (Covoes), Quinta dos Vales, Sao Martinho do
Bispo, Coimbra 3041-801, Portugal
Title
Collagen implant with gentamicin sulphate reduces surgical site infection
in vascular surgery: A prospective cohort study.
Source
International Journal of Surgery. 12 (10) (pp 1100-1104), 2014. Date of
Publication: 01 Oct 2014.
Publisher
Elsevier Ltd
Abstract
Surgical site infection (SSI) is a common complication after vascular
surgery. It may cause exposure of the underlying prosthesis causing graft
infection, which may require the removal of the vascular graft, increasing
amputation and mortality risks. Graft contamination usually occurs during
operative procedure or by direct spread from an infected wound. It is
therefore advisable to a strong effort in reducing SSI. Topic antibiotics
have not been fully studied in vascular surgery, but collagen implant with
gentamicin sulphate has shown to reduce SSI in cardiac surgery,
orthopaedics, and general surgery procedures. Methods: Sixty (60)
non-diabetic and non-obese patients with lower limb ischaemia with
indication for femoropopliteal PTFE prosthetic bypass were allocated into
2 groups of 30 patients. A collagen implant impregnated with gentamicin
sulphate (Collatamp<sup></sup>) was applied in the groin incision adjacent
to the prosthesis in one group, and the other was a control group. The
same surgical team operated all patients. Szilagyi classification was
used. Results: There was no SSI (0% - 0/30) in the collagen implant with
gentamicin sulphate group, contrasting with 6 cases (20% - 6/30) of SSI
(grade I and II) in the control group (p=0.024). In-hospital day's data
shows a significant difference between the two groups (p=0.004) with a
mean of 5.66 days for implant group and 8.10 days for control group. There
was no SSI grade III. Conclusion: Collagen implant with gentamicin
sulphate (Collatamp<sup></sup>) reduces SSI in the groin incision in
ischaemic patients submitted to femoropopliteal PTFE prosthetic bypass.
Days of hospitalization are also reduced. Decreasing SSI rate and
in-hospital days, this implant may also reduce health care costs. Because
this is a small pilot study, a multicentre RCT is necessary for
validation.

<4>
Accession Number
2014838629
Authors
Al-Atassi T. Toeg H. Malas T. Lam B.-K.
Institution
(Al-Atassi, Toeg, Malas, Lam) Division of Cardiac Surgery, University of
Ottawa Heart Institute, Ottawa, ON, Canada
Title
Mapping and ablation of autonomic ganglia in prevention of postoperative
atrial fibrillation in coronary surgery: Maappafs atrial fibrillation
randomized controlled pilot study.
Source
Canadian Journal of Cardiology. 30 (10) (pp 1202-1207), 2014. Date of
Publication: 01 Oct 2014.
Publisher
Pulsus Group Inc.
Abstract
Background: Postoperative atrial fibrillation (POAF) remains common after
coronary artery bypass grafting (CABG). Limited efforts to intervene on
cardiac autonomic ganglionic plexi (AGP) during surgery show mixed
results. In this pilot study, we evaluated the safety and feasibility of
map-guided ablation of AGPs during isolated CABG in the prevention of
POAF. Methods: In this pilot study, patients undergoing isolated CABG were
randomized into an intervention group (mapping and ablation of AGP [AGP+]
group), and a control group (no mapping and ablation [AGP-] group). Using
high-frequency stimulation, active AGPs were identified and ablated
intraoperatively using radiofrequency. Continuous rhythm monitoring, serum
electrolytes, postoperative medications, and postoperative complications
were recorded until discharge. Results: Randomization of 47 patients (24
AGP+ and 23 AGP-) resulted in similar baseline characteristics, past
medical history, and preoperative medication use. The intervention added a
median of 14 minutes to the operative time. The incidence of POAF, mean
time inPOAF, and median length of stay in hospital were: AGP+ 21% vs AGP-
30%; AGP+ 298 minutes vs AGP- 514 minutes; AGP+ 5 days vs AGP- 6 days;
respectively). Postoperative complications, medication use, and daily
serum electrolyte profiles were similar in both groups. Conclusions: This
pilot study demonstrated the safety and feasibility of mapping and
ablation of AGP during CABG with minimal added operative time. Results
further suggest a potentially clinically significant effect on POAF. A
multicentre trial is warranted.

<5>
Accession Number
2014837907
Authors
Johnson N.P. Toth G.G. Lai D. Zhu H. Acar G. Agostoni P. Appelman Y.
Arslan F. Barbato E. Chen S.-L. Di Serafino L. Dominguez-Franco A.J.
Dupouy P. Esen A.M. Esen O.B. Hamilos M. Iwasaki K. Jensen L.O.
Jimenez-Navarro M.F. Katritsis D.G. Kocaman S.A. Koo B.-K. Lopez-Palop R.
Lorin J.D. Miller L.H. Muller O. Nam C.-W. Oud N. Puymirat E. Rieber J.
Rioufol G. Rodes-Cabau J. Sedlis S.P. Takeishi Y. Tonino P.A.L. Van Belle
E. Verna E. Werner G.S. Fearon W.F. Pijls N.H.J. De Bruyne B. Gould K.L.
Institution
(Johnson, Gould) Weatherhead PET Center, University of Texas Medical
School at Houston, 6431 Fannin Street, Houston, TX 77030, United States
(Toth, Barbato, De Bruyne) Cardiovascular Center Aalst, Aalst, Belgium
(Lai, Zhu) Division of Biostatistics, University of Texas, School of
Public Health, Houston, TX, United States
(Acar, Esen) Department of Cardiology, Kartal Kosuyolu High Speciality
Education and Research Hospital, Istanbul, Turkey
(Agostoni, Arslan) Department of Cardiology, University Medical Center
Utrecht, Utrecht, Netherlands
(Appelman, Oud) Department of Cardiology, VU University Medical Center,
Amsterdam, Netherlands
(Chen) Department of Cardiology, Nanjing First Hospital, Nanjing Medical
University, Nanjing City, China
(Di Serafino) Department of Cardiology, Presidio Ospedaliero (P.O.) di
Venere, Bari, Italy
(Dominguez-Franco, Jimenez-Navarro) Unidad de Gestion Clinica Del Corazon,
Hospital Clinico Universitario Virgen de la Victoria, Universidad de
Malaga (UMA), Malaga, Spain
(Dupouy) Pole Cardiovasculaire Interventionnel, Hopital Prive d'Antony,
Antony, France
(Esen) Department of Cardiology, Memorial Hospital, Istanbul, Turkey
(Hamilos) Department of Cardiology, University Hospital of Heraklion,
Crete, Greece
(Iwasaki) Department of Cardiology, Okayama Kyokuto Hospital, Okayama,
Japan
(Jensen) Department of Cardiology, Odense University Hospital, Odense,
Denmark
(Katritsis) Department of Cardiology, Athens Euroclinic, Athens, Greece
(Kocaman) Department of Cardiology, Gazi University, School of Medicine,
Ankara, Turkey
(Koo) Department of Internal Medicine, Seoul National University Hospital,
Seoul, South Korea
(Lopez-Palop) Seccion de Cardiologia, Hospital Universitario San Juan,
Alicante, Spain
(Lorin, Sedlis) VA New York Harbor Health Care System, New York
University, School of Medicine, New York, NY, United States
(Miller) Department of Medicine, New York University, School of Medicine,
New York, NY, United States
(Muller) Department of Cardiology, University of Lausanne Hospital Center
(CHUV), Lausanne, Switzerland
(Nam) Department of Internal Medicine, Keimyung University Dongsan Medical
Center, Daegu, South Korea
(Puymirat) Hopital Europeen Georges Pompidou, Paris, France
(Rieber) Clinic for Cardiology and Internal Intensive Care Medicine,
Klinikum Bogenhausen, Munich, Germany
(Rioufol) Interventional Cardiology Department, Hospices Civils de Lyon,
INSERM 1060, France
(Rodes-Cabau) Quebec Heart and Lung Institute, Laval University, Quebec
City, Canada
(Takeishi) Department of Cardiology and Hematology, Fukushima Medical
University, Fukushima, Japan
(Tonino, Pijls) Department of Cardiology, Catharina Hospital, Eindhoven,
Netherlands
(Tonino, Pijls) Department of Biomedical Engineering, Eindhoven University
of Technology, Eindhoven, Netherlands
(Van Belle) Department of Cardiology, University Hospital,
Lille-II-University, Lille, France
(Verna) Department of Cardiology, Ospedale di Circolo e Fondazione Macchi,
University Hospital, Varese, Italy
(Werner) Klinikum Darmstadt, Darmstadt, Germany
(Fearon) Division of Cardiovascular Medicine, Stanford University Medical
Center, Stanford, CA, United States
Title
Prognostic value of fractional flow reserve: Linking physiologic severity
to clinical outcomes.
Source
Journal of the American College of Cardiology. 64 (16) (pp 1641-1654),
2014. Date of Publication: 21 Oct 2014.
Publisher
Elsevier USA
Abstract
Conclusions FFR demonstrates a continuous and independent relationship
with subsequent outcomes, modulated by medical therapy versus
revascularization. Lesions with lower FFR values receive larger absolute
benefits from revascularization. Measurement of FFR immediately after
stenting also shows an inverse gradient of risk, likely from residual
diffuse disease. An FFR-guided revascularization strategy significantly
reduces events and increases freedom from angina with fewer procedures
than an anatomy-based strategy. (J Am Coll Cardiol 2014;64:164154).

<6>
Accession Number
2014731352
Authors
Schwalm J.D.R. Wijeysundera H.C. Tu J.V. Guo H. Kingsbury K.J. Natarajan
M.K.
Institution
(Schwalm, Natarajan) McMaster University, Hamilton Health
Sciences/Population Health Research Institute, Hamilton, ON, Canada
(Wijeysundera, Tu) Sunnybrook Health Sciences Centre, Toronto, ON, Canada
(Wijeysundera, Tu, Guo) Institute for Clinical Evaluative Sciences,
Toronto, ON, Canada
(Kingsbury) Cardiac Care Network, Toronto, ON, Canada
Title
Influence of coronary anatomy and SYNTAX score on the variations in
revascularization strategies for patients with multivessel disease.
Source
Canadian Journal of Cardiology. 30 (10) (pp 1155-1161), 2014. Date of
Publication: 01 Oct 2014.
Publisher
Pulsus Group Inc.
Abstract
Background: The Variation in Revascularization Practice in Ontario (VRPO)
project helped describe variations in revascularization across Ontario.
Coronary anatomy was the most important predictor of revascularization
strategy. We conducted a novel angiographic substudy of the VRPO cohort
to: (1) validate "real-world" coronary angiographic reporting in the
province of Ontario; and (2) understand the relationship between
variability in revascularization and coronary anatomy complexity. Methods:
Seventeen hundred eighty-seven angiograms from 17 cardiac centres were
randomly sampled from the VRPO cohort. The core lab assessment involved
blinded interpretation of each angiographic film. A comparison of
agreement in coronary anatomy and treatment strategy between abstracted
chart data from the VRPO study and blinded film review was undertaken.
Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac
Surgery (SYNTAX) scores were calculated for all patients with multivessel
disease. Results: The weighted statistic for coronary anatomy was 0.75
(95% confidence interval, 0.72-0.77), suggesting substantial agreement
between abstracted chart data and blinded film review. The weighted for
revascularization strategy was 0.51 (95% confidence interval, 0.47-0.54)
suggesting only moderate agreement. There were no significant differences
in the mean/median SYNTAX scores across all 4 percutaneous coronary
intervention: coronary artery bypass graft (CABG) groups. Conclusions:
Abstracted chart data in the VRPO project provides a valid assessment of
coronary anatomy and furthermore serves as validation of "real-world"
coronary angiographic reporting in the province of Ontario. The uniform
distribution of coronary complexity across centres in Ontario, with
respect to the SYNTAX score, suggests the variation of percutaneous
coronary intervention: CABG ratio is not related to a difference in
coronary anatomy complexity across sites, but rather a difference in
management strategies for the same anatomy.

<7>
Accession Number
2014832889
Authors
Elsisi G.H. Eldessouki R. Kalo Z. Elmazar M.M. Taha A.S. Awad B.F.
El-Hamamsy M.H.
Institution
(Elsisi) Pharmacoeconomic Unit, Central Administration for Pharmaceutical
Affairs, Cairo, Egypt
(Eldessouki) Scientific and Health Policy Initiatives, International
Society for Pharmacoeconomics and Outcomes Research, NJ, United States
(Eldessouki) Faculty of Medicine, Fayoum University, Al Fayoum, Egypt
(Kalo) Health Economics Research Centre, Eotvos Lorand University,
Budapest, Hungary
(Elmazar) Faculty of Pharmacy, The British University in Egypt (BUE), El
Sherouk, Cairo, Egypt
(Taha, Awad) Faculty of Medicine, Ain Shams University, Cairo, Egypt
(Taha, Awad) Cardiothoracic Surgery Unit, Ain Shams University Hospitals,
Cairo, Egypt
(El-Hamamsy) Faculty of Pharmacy, Ain Shams University, Cairo, Egypt
Title
Cost-Effectiveness of the Combined Use of Warfarin and Low-Dose Aspirin
versus Warfarin Alone in Egyptian Patients with Aortic Valve Replacements:
A Markov Model.
Source
Value in Health Regional Issues. 4 (pp 24-30), 2014. Date of Publication:
December 01, 2014.
Publisher
Elsevier Inc.
Abstract
Background: The combination of antiplatelet and anticoagulant therapy
significantly reduces the rate of thromboembolic events in patients with
heart valves compared with anticoagulant therapy alone. Cost-effectiveness
of this therapy in Egypt, however, has not yet been established.
Objective: The aim of the present study was to evaluate the
cost-effectiveness of the combined use of warfarin and low-dose aspirin
(100 mg) versus warfarin alone in patients with mechanical aortic heart
valve prostheses who began therapy at the age of 50 to 60 years over a
5-year period from the perspective of the medical providers. Methods: A
cohort Markov process model with five health states (recovery,
reoperation, bleeding, thromboembolism, and death) based on Egyptian
clinical practice was derived from published sources. The clinical
parameters were derived from meta-analyses of randomized controlled trials
of patients with mechanical valve prostheses. The quality of life of the
health states was derived using the available published data. Direct
medical costs were obtained from four top-rated governmental cardiology
hospitals in Egypt. All costs and effects were discounted at 3.5%
annually. All costs were converted using the purchasing power parity rate
and are reported in US $ for the financial year of 2013. Results: The
total quality-adjusted life-years (QALYs) were estimated to be 1.1616 and
1.1199 for the warfarin plus aspirin group and the warfarin group,
respectively, which resulted in a difference of 0.0416 QALYs. The total
costs for the warfarin plus aspirin group and the warfarin group were US
$307.33 and US $315.25, respectively (the difference was US $7.92), which
yielded an incremental cost-effectiveness ratio of -190.38 for the
warfarin plus aspirin group. Thus, the combined therapy was dominant.
Various one-way sensitivity analyses indicated that probabilities of
reoperation and bleeding in the recovery state had the greatest effects on
incremental costs. The model parameters that had the greatest effects on
incremental QALYs were the relative risk reduction of death and the
utility value in the recovery state. Conclusions: The present study is the
first cost-utility analysis to conclude that, from the perspective of
Egyptian medical providers, combined therapy is more effective and less
costly than warfarin alone for patients with mechanical aortic valve
prostheses. For clinicians and patients who choose to focus on minimizing
thromboembolic risk, these results suggest that combined therapy offers
the best protection. This study helps to inform decisions about the
allocation of health care system resources and to achieve better health in
the Egyptian population.

<8>
Accession Number
2014829760
Authors
Badiee P. Amirghofran A.A. Nour M.G.
Institution
(Badiee) Alborzi Clinical Microbiology Research Center, Shiraz, Iran,
Islamic Republic of
(Amirghofran, Nour) Cardiothoracic Surgery Unit, Shiraz University of
Medical Sciences, Shiraz, Iran, Islamic Republic of
Title
Evaluation of noninvasive methods for the diagnosis of fungal
endocarditis.
Source
Medical Mycology. 52 (5) (pp 528-534), 2014. Date of Publication: 2014.
Publisher
Oxford University Press
Abstract
Fungal endocarditis (FE) is an uncommon disease with a high risk of
morbidity and mortality. Here, we evaluated the different methods for
diagnosing this infection. Cardiac valve, vegetation, and embolic
materials obtained during surgery were examined for fungal infections by
direct smear and culture. At least two blood samples were inoculated at
the bedside into BACTEC medium. Galactomannan, mannan Ag enzyme-linked
immunosorbent assay, and real-time polymerase chain reaction (PCR) assay
were performed with serum samples. Of 25 patients with suspected infective
endocarditis (IE), 8 were found to have proven FE according to the direct
culture results. The etiologic agents were Aspergillus niger (three
cases), A. flavus (two cases), A. fumigatus (one case), and Candida
albicans (two cases). Blood culture was positive in only 1 case. The
sensitivity, specificity, positive and negative predictive values, and
positive and negative likelihood ratios of the results from the
galactomannan test were 83.3%, 84.2%, 62.5%, 94.1%, 5.3, and 0.2; these
same values, obtained from real-time PCR, were 87.5%, 94.4%, 87.5%, 94.4%,
15.6, and 0.14, respectively. Because mannan antigen was positive in
samples from only one patient, we opted not to calculate the sensitivity.
However, the specificity value in 23 cases without IE caused by Candida
spp.was 100%. Based on our results, both the galactomannan test and
real-time PCR can serve as reliable, noninvasive tests for the diagnosis
of FE, compared with culture, which is considered to be the gold standard.

<9>
Accession Number
2014833720
Authors
Bathini L. Jomah M. Krajacic A. Jeffery C. Campbell S. El-Hakim H.
Institution
(El-Hakim) Pediatric Otolaryngology Service, The Stollery Children's
Hospital and The University of Alberta Hospitals, Edmonton, AB, Canada
(Jomah, Jeffery, El-Hakim) Division of Otolaryngology - Head and Neck
Surgery, The Stollery Children's Hospital and The University of Alberta
Hospitals, Edmonton, AB, Canada
(El-Hakim) Division of Pediatric Surgery, The Stollery Children's Hospital
and The University of Alberta Hospitals, Edmonton, AB, Canada
(Jomah, Krajacic, Jeffery) Department of Surgery, The Stollery Children's
Hospital and The University of Alberta Hospitals, Edmonton, AB, Canada
(Campbell) Department of Pediatrics, The Stollery Children's Hospital and
The University of Alberta Hospitals, Edmonton, AB, Canada
(Bathini, Krajacic) John W. Scott Health Science Library, University of
Alberta, Edmonton, AB, Canada
(El-Hakim) Faculty of Medicine and Dentistry, University of Alberta,
Edmonton, AB, Canada
Title
Acquired bilateral adductor laryngeal paralysis in neonates and children:
A case series and a systematic review.
Source
International Journal of Pediatric Otorhinolaryngology. 78 (11) (pp
1866-1869), 2014. Date of Publication: 01 Nov 2014.
Publisher
Elsevier Ireland Ltd
Abstract
Objectives: To present a series of acquired bilateral adductor laryngeal
paralysis (BAdLP) and review the literature on clinical manifestations and
management. Methods: A retrospective review of a single tertiary care
practice of pediatric otolaryngology was conducted. Patients were
identified from a surgical database spanning twelve years of practice
(2002-2013). The variables documented included gender, age at
presentation, co-morbid conditions, documented laryngeal findings on
endoscopy, management and outcome. A systematic review of the literature
was conducted to identify reports on BAdLP in children and associated
conditions. Results: Five cases (four girls and one boy) ranging from 3
months to 16 years of age were identified. All cases were documented using
rigid and/or flexible laryngoscopy. In four cases, the onset was after
major cardiac surgery complicated by cerebral vascular accidents, while
one followed a thalamic stroke. Four were managed with tube feeding. Only
three papers reported BAdLP in children. Conclusions: The cases identified
were all acquired after a central neurological insult. The profile is
distinct from the congenital adductor form of laryngeal paralysis
previously described. However, the symptom complex is identical. We
believe this is the largest case series from one center to be reported.

<10>
Accession Number
2014817782
Authors
Pedersen P.U. Larsen P. Hakonsen S.J. Christensen B.N.
Institution
(Pedersen) Danish Centre of Systematic Reviews in Nursing: An affiliate
centre of The Joanna Briggs Institute, The Centre of Clinical Guidelines -
Danish National Clearing house for Nursing, Hoegh-Guldbergs Gade 6A,
Arhusc 8000, Denmark
(Larsen, Hakonsen) Danish Centre of Systematic Reviews in Nursing, Denmark
(Christensen) Library of Health Sciences, University of Aarhus, Denmark
Title
The effectiveness of perioperative oral hygiene in reduction of
postoperative respiratory tract infections after thoracic surgery in
adults: A systematic review.
Source
JBI Database of Systematic Reviews and Implementation Reports. 10 (pp
S200-S211), 2012. Date of Publication: 2012.
Publisher
Joanna Briggs Institute
Abstract
Review question/objective: The objective of this systematic review is to
identify, appraise and synthesise the best available evidence on the
effectiveness of systematic perioperative oral hygiene in reduction of
post-operative respiratory airway infections in adult patients undergoing
elective thoracic surgery.

<11>
Accession Number
2014817805
Authors
Godfrey C. Maylin S. Ross-White A.
Institution
(Godfrey) The Queen's Joanna Briggs Collaboration for Patient Safety: A
collaborating centre of the Joanna Briggs Institute (QJBC), Queen's
University, Kingston, ON, Canada
(Maylin) Queen's University, Canada
(Ross-White) Bracken Library Queen's University, Canada
Title
Transforming self- the experience of living with another's heart: A
systematic review of qualitative evidence on adult heart transplantation.
Source
JBI Database of Systematic Reviews and Implementation Reports. 10 (pp
S273-S282), 2012. Date of Publication: 2012.
Publisher
Joanna Briggs Institute
Abstract
2. How do heart recipients cope with the loss of their own heart and how
do they reach acceptance of their donor heart?

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